Rosacea acne caused by faulty immune response, not bacteria, say researchers

Rosacea, a skin condition affecting an estimated 45 million people worldwide, is now thought to be caused by an overly zealous immune response, and not bacteria.
Researchers at the University of California at San Diego found
…that “too much stratum corneum tryptic enzyme and too much cathelicidin leads to the abnormal peptides that cause the symptoms of this disease,” Dr. Gallo said.
“Antibiotics tend to alleviate the symptoms of rosacea in patients because some of them work to inhibit these enzymes,” he noted. “Our findings may modify the therapeutic approach to treating rosacea, since bacteria aren’t the right target.”
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